Cellulose Acetate Phthalate Microencapsulation and Delivery of Plasmid DNA to the Intestines

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Cellulose acetate phthalate microencapsulation and delivery of plasmid DNA to the intestines.

Cellulose acetate phthalate (CAP) microcapsules were formulated to deliver plasmid DNA (pDNA) to the intestines. The microcapsules were characterized and were found to have an average diameter of 44.33 ± 30.22 μm, and were observed to be spherical with smooth surface. The method to extract pDNA from CAP was modified to study the release profile of the pDNA. The encapsulated pDNA was found to be...

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ژورنال

عنوان ژورنال: Journal of Pharmaceutical Sciences

سال: 2013

ISSN: 0022-3549

DOI: 10.1002/jps.23389